Prostate Cancer

Prostate cancer affects more than 200,000 men a year in the United States, with 30,000 men dying each year from advanced prostate cancer. In the last ten years, there has been a 25% decline in mortality, most likely due to early detection and aggressive treatment.

Unlike other disease processes, there are many different treatment options offered by various disciplines in medicine/surgery. The urologist is generally the first doctor a patient will encounter with prostate cancer. Treatment of prostate cancer in Minneapolis is a complex process involving many factors. One must balance the stage and grade of the cancer with the patient’s age, health and personal situation.

We are one of the few urology practices in the area to have an MRI / Ultrasound guided biopsy for men who have had rising PSA and negative biopsies.

Patients at Minnesota Urology now have access to UroNav, which is an MRI assisted, ultrasound-guided biopsy technique which provides a new level of accuracy to the detection of prostate cancer. Because it can detect prostate cancers in hard to find areas of the prostate, UroNav can reduce the need for multiple biopsies and find cancers in men with previous negative biopsies.

UroNav is a new high tech approach to the diagnosis of prostate cancer. UroNav testing has already found aggressive prostate cancers in men with previous negative biopsies.

There are six different options available for the treatment of prostate cancer:

“Watchful waiting” is a good option for men in poor health, elderly or select patients with early prostate cancer. Untreated prostate cancer may take years to progress to metastatic disease. Careful monitoring of the PSA and the patient’s condition are performed. Any changes usually lend to a more aggressive option.

Radiation Therapy is the use of high-energy rays to kill prostate cancer cells. Radiation therapy is used for both local disease and to palliate advanced disease. There are two standard forms of radiation, external beam radiation and brachytherapy;


LHRH analogs (luteinizing hormone-releasing hormone) a drug that prevents testosterone production by the testis

Nonsteroidal antiandrogens – a class of drug, which blocks the action of testosterone at the prostate


Chemotherapy drugs are given intravenously that destroy prostate cancer cells. Often chemotherapy is used in advanced hormonal refractory prostate cancer. Traditionally, chemotherapy is the last line of defense against prostate cancer.

Prostate cancer is the most common malignancy in men other than skin cancer. This means that thousands of men each year are faced with an important life decision. The prostate cancer treatment approaches are many; therefore it is critical that multiple factors are considered prior to recommending treatment. A patient’s age, health status, and lifestyle wishes all need to be considered carefully, and the patient and his family need to be well informed of all of the treatment options. The art of medicine, taking all of these factors into account, can become as important as the science of medicine. Yet, through a careful and thoughtful approach, the patient can receive aggressive, effective yet appropriate treatment for their particular situation and disease state.

HIFU: High Intensity Frequency Ultrasound(HIFU) is a highly effective treatment option for the eradication of prostate cancer. There is 10 year data supporting its effectiveness and minimal side effects. Dr. Jeffry Twidwell, a urologist at Minnesota Urology has been very pleased with the results of HIFU. “Patients experience very little pain and are up and active within hours of the procedure. Prostate cancer control has been achieved with few side effects. HIFU has provided a treatment option that addresses both cancer control and quality of life. It truly is a win-win”.

Robotic Surgery for Prostate Cancer

Since its introduction in 2004, the providers at Minnesota Urology have completed more than 10,000 successful da Vinci® prostatectomy surgeries in at hospitals all around the state including: United Hospital, North Memorial Hospital, Regions Hospital, Abbott Northwestern Hospital, Mercy Hospital, St. John’s, and Fairview Southdale Hospital. 

By integrating robotic technology with our surgeon’s skill, the da Vinci® System enables surgeons to perform precise minimally invasive, nerve sparring surgery in a manner never before experienced to enhance healing and promote well-being. This operation represents a significant advance in our treatment for prostate cancer patients and we are delighted to offer this service to our patients.